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Six teams seek to identify biological factors that influence neural regeneration

Thu, 09/01/2016 - 01:38

The National Institutes of Health will fund six projects to identify biological factors that affect neural regeneration in the retina. The projects are part of the National Eye Institute (NEI) Audacious Goals Initiative (AGI), a targeted effort to restore vision by regenerating neurons and their connections in the eye and visual system. These projects will receive a total of $12.4 million over three years, pending availability of funds. 

Six teams seek to identify biological factors that influence neural regeneration

Thu, 09/01/2016 - 01:38

The National Institutes of Health will fund six projects to identify biological factors that affect neural regeneration in the retina. The projects are part of the National Eye Institute (NEI) Audacious Goals Initiative (AGI), a targeted effort to restore vision by regenerating neurons and their connections in the eye and visual system. These projects will receive a total of $12.4 million over three years, pending availability of funds. 

Six teams seek to identify biological factors that influence neural regeneration

Thu, 09/01/2016 - 01:38

The National Institutes of Health will fund six projects to identify biological factors that affect neural regeneration in the retina. The projects are part of the National Eye Institute (NEI) Audacious Goals Initiative (AGI), a targeted effort to restore vision by regenerating neurons and their connections in the eye and visual system. These projects will receive a total of $12.4 million over three years, pending availability of funds. 

Drugs already on market prevent light-induced retinal degeneration in mice

Thu, 08/04/2016 - 22:10

Combinations of Food and Drug Administration-approved drugs protect against the loss of cells required for vision in a mouse model of blinding retinal diseases. The study, published in Science Signaling, was funded by the National Eye Institute, a part of the National Institutes of Health.

Drugs already on market prevent light-induced retinal degeneration in mice

Thu, 08/04/2016 - 22:10

Combinations of Food and Drug Administration-approved drugs protect against the loss of cells required for vision in a mouse model of blinding retinal diseases. The study, published in Science Signaling, was funded by the National Eye Institute, a part of the National Institutes of Health.

Use it or Lose it: Visual Activity Regenerates Neural Connections Between Eye and Brain

Fri, 07/08/2016 - 14:05

A study in mice funded by the National Institutes of Health (NIH) shows for the first time that high-contrast visual stimulation can help damaged retinal neurons regrow optic nerve fibers, otherwise known as retinal ganglion cell axons. In combination with chemically induced neural stimulation, axons grew further than in strategies tried previously. Treated mice partially regained visual function. The study also demonstrates that adult regenerated central nervous system (CNS) axons are capable of navigating to correct targets in the brain.

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Use it or Lose it: Visual Activity Regenerates Neural Connections Between Eye and Brain

Fri, 07/08/2016 - 14:05

A study in mice funded by the National Institutes of Health (NIH) shows for the first time that high-contrast visual stimulation can help damaged retinal neurons regrow optic nerve fibers, otherwise known as retinal ganglion cell axons. In combination with chemically induced neural stimulation, axons grew further than in strategies tried previously. Treated mice partially regained visual function. The study also demonstrates that adult regenerated central nervous system (CNS) axons are capable of navigating to correct targets in the brain.

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NEI Scientist Receives Research Grant from Knights Templar Eye Foundation

Fri, 07/01/2016 - 15:12

NEI research fellow Nathan Hotaling, PhD, has been awarded a $65,000 grant from the Knights Templar Eye Foundation to develop a stem cell-based system to study Best disease, a genetic disorder that can cause progressive vision loss. The system will allow researchers to develop tests to monitor cellular changes that lead to Best disease, which typically starts in childhood.

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NEI Scientist Receives Research Grant from Knights Templar Eye Foundation

Fri, 07/01/2016 - 15:12

NEI research fellow Nathan Hotaling, PhD, has been awarded a $65,000 grant from the Knights Templar Eye Foundation to develop a stem cell-based system to study Best disease, a genetic disorder that can cause progressive vision loss. The system will allow researchers to develop tests to monitor cellular changes that lead to Best disease, which typically starts in childhood.

Language English

NIH Vision Scientists Test Theory of How Rods in our Retina Originated

Mon, 06/20/2016 - 17:27

Retinas from our earliest vertebrate ancestors had cone-like photoreceptors, presumably allowing them to see in daylight, but little ability to see at night. Then, millions of years ago in the Mesozoic era, and in relatively short order, mammals emerged that had retinas with predominantly rod photoreceptors, allowing for them to see at night perhaps to hunt for food while their dinosaur predators were dozing. Now a new study led by researchers the National Eye Institute suggests how the genesis of rod photoreceptors may have occurred to give rise to nocturnal mammals.

NIH Vision Scientists Test Theory of How Rods in our Retina Originated

Mon, 06/20/2016 - 17:27

Retinas from our earliest vertebrate ancestors had cone-like photoreceptors, presumably allowing them to see in daylight, but little ability to see at night. Then, millions of years ago in the Mesozoic era, and in relatively short order, mammals emerged that had retinas with predominantly rod photoreceptors, allowing for them to see at night perhaps to hunt for food while their dinosaur predators were dozing. Now a new study led by researchers the National Eye Institute suggests how the genesis of rod photoreceptors may have occurred to give rise to nocturnal mammals.

NEI Welcomes Four New Members to National Advisory Eye Council

Wed, 06/15/2016 - 17:34

Today four new members join the National Advisory Eye Council, an advisory body for the National Eye Institute (NEI) at NIH. The council provides advice to guide NEI research and training programs.

“NEI welcomes these new appointees; the breadth of their expertise will be invaluable,” said NEI director Paul A. Sieving, M.D., Ph.D. “We look forward to receiving their guidance as we continue to advance vision research, translating discoveries into treatments and therapies for patients.”

The four new council members are:




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NEI Welcomes Four New Members to National Advisory Eye Council

Wed, 06/15/2016 - 17:34

Today four new members join the National Advisory Eye Council, an advisory body for the National Eye Institute (NEI) at NIH. The council provides advice to guide NEI research and training programs.

“NEI welcomes these new appointees; the breadth of their expertise will be invaluable,” said NEI director Paul A. Sieving, M.D., Ph.D. “We look forward to receiving their guidance as we continue to advance vision research, translating discoveries into treatments and therapies for patients.”

The four new council members are:




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Eye Study Underscores the Long-lasting Benefits of Controlling Diabetes

Fri, 06/10/2016 - 15:15

People with type 2 diabetes who intensively controlled their blood sugar level during the landmark Action to Control Cardiovascular Risk in Diabetes (ACCORD) Trial Eye Study were found to have cut their risk of diabetic retinopathy in half in a follow-up analysis conducted four years after stopping intensive therapy. Investigators who led the ACCORD Follow-on Eye Study (ACCORDION) announced the results today in New Orleans at the American Diabetes Association annual meeting. The study was supported by the National Institutes of Health’s National Eye Institute (NEI).

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Visual impairment, blindness cases in U.S. expected to double by 2050

Wed, 05/18/2016 - 19:07

With the youngest of the baby boomers hitting 65 by 2029, the number of people with visual impairment or blindness in the United States is expected to double to more than 8 million by 2050, according to projections based on the most recent census data and from studies funded by the National Eye Institute, part of the National Institutes of Health. Another 16.4 million Americans are expected to have difficulty seeing due to correctable refractive errors such as myopia (nearsightedness) or hyperopia (farsightedness) that can be fixed with glasses, contacts or surgery.

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