Cystic fibrosis is a common inherited condition, particularly affecting people from a northern European background.  It's caused by various mutations of the Cystic Fibrosis Transmembrane Conductance Regulator gene, shortened to "CFTR".  A new Cochrane Review from August 2018 examines a class of drug that aims to correct the basic defect for people with CF with a specific mutation, and we asked lead author, Kevin Southern from the University of Liverpool in the UK, to tell us what they found.

There are concerns across the world about the rising incidence of type 2 diabetes, increasing the importance of evidence for effective ways to prevent this condition. In a December 2017 update to the Cochrane Review, Bianca Hemmingsen from Herlev University Hospital in Denmark and colleagues have summarized the latest evidence on the effects of diet and physical activity for people with intermediate hyperglycaemia or prediabetes. We asked Bianca to tell us what they found in this podcast.

There are concerns across the world about the rising incidence of type 2 diabetes, increasing the importance of evidence for effective ways to prevent this condition. In a December 2017 update to the Cochrane Review, Bianca Hemmingsen from Herlev University Hospital in Denmark and colleagues have summarized the latest evidence on the effects of diet and physical activity for people with intermediate hyperglycaemia or prediabetes. We asked Bianca to tell us what they found in this podcast.

The Cochrane Drugs and Alcohol Group specialises in reviews that assess, among other things, ways to reduce hazardous or harmful drinking of alcohol. One of these reviews looks at the evidence on practitioner-delivered brief interventions and we asked one of the authors, Fiona Beyer from Newcastle University in the UK to tell us about the findings from the update in February 2018.

The Cochrane Drugs and Alcohol Group specialises in reviews that assess, among other things, ways to reduce hazardous or harmful drinking of alcohol. One of these reviews looks at the evidence on practitioner-delivered brief interventions and we asked one of the authors, Fiona Beyer from Newcastle University in the UK to tell us about the findings from the update in February 2018.

As you can imagine, placing a breathing tube into a newborn baby is a particularly challenging task, and research has been done into different ways to do this. In May 2018, Mohan Pammi and Krithika Lingappan from Baylor College of Medicine in Houston in the USA updated the Cochrane review on comparing videolaryngoscopy to the traditional direct laryngoscopy approach and they describe the latest findings in this podcast, starting with Mohan.

As you can imagine, placing a breathing tube into a newborn baby is a particularly challenging task, and research has been done into different ways to do this. In May 2018, Mohan Pammi and Krithika Lingappan from Baylor College of Medicine in Houston in the USA updated the Cochrane review on comparing videolaryngoscopy to the traditional direct laryngoscopy approach and they describe the latest findings in this podcast, starting with Mohan.

The Cochrane Gynaecology and Fertility Group has prepared more than 200 reviews and in May 2018, a team from Germany, The Netherlands and New Zealand updated one of these reviews, looking at the use of letrozole for subfertile women with anovulatory polycystic ovary syndrome. Lead author, Sebastian Franik from the University of Münster in Germany describes the latest findings in this podcast.

The Cochrane Gynaecology and Fertility Group has prepared more than 200 reviews and in May 2018, a team from Germany, The Netherlands and New Zealand updated one of these reviews, looking at the use of letrozole for subfertile women with anovulatory polycystic ovary syndrome. Lead author, Sebastian Franik from the University of Münster in Germany describes the latest findings in this podcast.

Urinary incontinence is a distressing condition for which there are a variety of treatment options. June Cody from the Cochrane Incontinence Group and colleagues have investigated the effects of a particular type of surgery and updated their review in July 2017. Here’s June to tell us what they found.

A variety of approaches have been suggested for reducing muscle soreness after exercise, one of which is to use antioxidant supplements. A new Cochrane Review from December 2017 brought together the evidence from the relevant research and lead author, Mayur Ranchordas from Sheffield Hallam University in the UK, tells us what they found in this podcast.

Coping with the increasing number of people with dementia is likely to be one of the major challenges for health systems globally in coming years and decades. There are several Cochrane Reviews of ways to treat or alleviate this condition and an updated review in March 2018 looks at the evidence for reminiscence therapy. We asked lead author, Bob Woods from Bangor University in Wales, to summarise the findings in this podcast.

 Urinary incontinence is a distressing condition for which there are a variety of treatment options. June Cody from the Cochrane Incontinence Group and colleagues have investigated the effects of a particular type of surgery. They updated the review's findings on the effects of the operations in 2015, and published an extension in July 2017, to include more on the economic aspects. Here's June to tell us about the evidence on the clinical effects.

A variety of approaches have been suggested for reducing muscle soreness after exercise, one of which is to use antioxidant supplements. A new Cochrane Review from December 2017 brought together the evidence from the relevant research and lead author, Mayur Ranchordas from Sheffield Hallam University in the UK, tells us what they found in this podcast.

Coping with the increasing number of people with dementia is likely to be one of the major challenges for health systems globally in coming years and decades. There are several Cochrane Reviews of ways to treat or alleviate this condition and an updated review in March 2018 looks at the evidence for reminiscence therapy. We asked lead author, Bob Woods from Bangor University in Wales, to summarise the findings in this podcast.

Many people vomit or feel nauseous after surgery, and it’s important to find effective ways to ease these unpleasant symptoms. One of the updated Cochrane Reviews in March 2018 looks at the effect of aromatherapy and we asked Sonia Hines from the Queensland Centre for Evidence‐Based Nursing & Midwifery in Australia to tell us more about the latest results.

More than half a dozen Cochrane Reviews have been done in various areas of health, to examine the evidence on the potential benefits of Selenium, a naturally occurring element with both nutritional and toxicological properties. The review looking at its possible role in the prevention of cancer was updated in January 2018 and one of the authors, Maree Brinkman from the Nutrition Biomed Research Institute in Melbourne in Australia. gives us the latest findings in this podcast.

The Cochrane Pain, Palliative and Supportive Care Group has been producing Cochrane Reviews for more than 20 years, including dozens covering a wide range of therapies for pain. In April 2018, their review of brain stimulation for chronic pain was updated and lead author Neil E O'Connell from Brunel University London in the UK tells us about the latest evidence in this podcast.

Many people vomit or feel nauseous after surgery, and it’s important to find effective ways to ease these unpleasant symptoms. One of the updated Cochrane Reviews in March 2018 looks at the effect of aromatherapy and we asked Sonia Hines from the Queensland Centre for Evidence‐Based Nursing & Midwifery in Australia to tell us more about the latest results.

More than half a dozen Cochrane Reviews have been done in various areas of health, to examine the evidence on the potential benefits of Selenium, a naturally occurring element with both nutritional and toxicological properties. The review looking at its possible role in the prevention of cancer was updated in January 2018 and one of the authors, Maree Brinkman from the Nutrition Biomed Research Institute in Melbourne in Australia. gives us the latest findings in this podcast.