Podcasts from The Cochrane Library

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Updated: 32 min 23 sec ago

Lidocaine for reducing propofol-induced pain on anaesthesia in adults

Tue, 09/20/2016 - 20:10

A February 2016 addition to the nearly 200 reviews from the Cochrane Anaesthesia, Critical and Emergency Care Group examines the evidence on lidocaine as a way to reduce the pain from using propofol to induce anaesthesia. Hayley Hassan, from the Cochrane Central Executive Team, describes the need for the review and its findings in this podcast, on behalf of the review authors.

Fluoride mouthrinses for preventing dental caries in children and adolescents

Thu, 09/15/2016 - 19:27

The Cochrane Oral Health Group has produced many reviews relevant to the prevention of tooth decay and, in July 2016, they updated their investigation of fluoride mouthrinses for children and adolescents. Helen Worthington, Co-ordinating Editor of the Group from the University of Manchester in the UK and one of the authors of this review, tells us what they found in this Evidence Pod.

Iron supplementation taken daily for improving health in menstruating women

Mon, 09/05/2016 - 16:22

In April 2016, Sant-Rayn Pasricha from the MRC Weatherall Institute of Molecular Medicine at the University of Oxford in the UK and colleagues from Australia and Canada published their new review on the use of iron supplementation by menstruating women, strengthening the collection of Cochrane evidence on the treatment of iron deficiency. He describes the latest findings in this evidence pod.

Which therapies are the most effective to prevent the progression of autosomal dominant polycystic kidney disease?

Mon, 09/05/2016 - 15:23

There is considerable interest in innovative treatments for adult polycystic kidney disease, in particular those treatments that might interrupt the biological processes that lead to cyst formation and kidney failure. It is important, therefore, to have good evidence of the effects of these treatments and, in a July 2015 Cochrane Review, Davide Bolignano from Reggio Calabria in Italy and colleagues examined the relevant studies to assess the effects on patient outcomes. Here’s Davide to tell us more.

Opioid maintenance medicines for the treatment of dependence on opioid pain medicines

Wed, 08/17/2016 - 03:55

Some patients who take pharmaceutical opioids to treat pain become dependent on these drugs, and might need to switch to medications such as opioid agonists. In May 2016, a new Cochrane Review brought together the relevant evidence on this and we asked Suzanne Nielsen from the National Drug and Alcohol Research Centre in Australia to tell us what they found.

Interventions for preventing abuse in the elderly

Tue, 08/16/2016 - 12:06

The typical Cochrane Review provides answers about the treatment of a disease but, occasionally, one comes along that tackles other major challenges facing society. One such new review in August 2016 looks at the evidence on various ways to prevent abuse in the elderly. Here’s one of the research team, Philip Baker from Queensland University of Technology in Australia to tell us what they found.

Fraction size in radiation therapy for breast conservation in early breast cancer

Tue, 08/16/2016 - 05:20

For many women with breast cancer, the use of post-operative radiotherapy will allow them to undergo less extensive surgery. In July 2016, Brigid Hickey from the Princess Alexandra Hospital in Brisbane Australia and colleagues published an update of their Cochrane Review examining the research on the size of the doses in which the radiation is given. She tells us what they found in this Evidence Pod.

Partial breast irradiation for early breast cancer

Tue, 08/16/2016 - 05:17

For many women with breast cancer, the use of post-operative radiotherapy will allow them to undergo less extensive surgery. In the update of a Cochrane Review in July 2016, Brigid Hickey and colleagues from the Princess Alexandra Hospital in Brisbane Australia examined the research on the use of partial breast irradiation and she tells us what they found in this Evidence Pod.

Can music interventions benefit cancer patients?

Mon, 08/15/2016 - 17:02

Music therapy is used for a variety of conditions and several Cochrane Reviews examine its effects. A team of music therapists with expertise in the use of music therapy with medical patients updated their review for cancer patients in August 2016 and Joke Bradt from the department of Creative Arts Therapies at Drexel University in Philadelphia, USA tells us what they found in this Evidence Pod. She conducted the review with Cheryl Dileo from Temple University in Philadelphia, Lucanne Magill from  Mount Sinai Hospital and New York University in New York, and Aaron Teague, doctoral student in the department of Creative Arts Therapies at Drexel University.

Vitamin A supplementation for postpartum women

Mon, 08/08/2016 - 14:47

The Cochrane Pregnancy and Childbirth Group have produced several reviews of the effects of vitamin supplements for pregnant women. Alongside these, in March 2016, researchers from Australia, Brazil and Germany updated the review of taking vitamin A supplementation after birth. One of the team, Christine East from Monash University in Australia, tells us more.

Different doses and durations of oral steroids for asthma attacks

Thu, 07/28/2016 - 19:34

Corticosteroids are a widely used treatment for asthma and a recent addition to the collection of Cochrane Reviews on this condition examines the research that compared different ways of using corticosteroids. Rebecca Normansell (left) and Kayleigh Kew from the Population Health Research Institute at St George's in the University of London in the UK describe the findings of this May 2016 review in this Evidence Pod, starting with Rebecca.

Treatments for chronic rhinosinusitis

Tue, 07/26/2016 - 16:16

Chronic rhinosinusitis is a common disorder of the nose and sinuses, and, in April 2016, the Cochrane ENT Group published a series of six reviews1 looking at the evidence on medical treatments in routine patient care. Carl Philpott from Norwich Medical School in the UK describes the findings of all six reviews in this Evidence Pod.

1 - List of reviews:

Strategies designed to help healthcare professionals to recruit participants to research studies

Fri, 07/08/2016 - 18:34

Alongside the thousands of Cochrane Reviews of the effects of health care, a couple of dozen Cochrane Methodology Reviews assess evidence relevant to the conduct of research. In this Evidence Pod, Nancy Preston from Lancaster University in England tells us about her February 2016 review which looks for ways to help healthcare practitioners recruit people to research studies.

Haemodiafiltration, haemofiltration and haemodialysis for end-stage kidney disease

Wed, 06/22/2016 - 14:13

There is considerable interest in innovative dialysis therapies for people with kidney failure, in particular to remove larger circulating toxins that are poorly removed by standard haemodialysis, which are associated with higher mortality and infection. In an updated Cochrane review, published in May 2015, Suetonia Palmer from Christchurch in New Zealand and colleagues, brought together the studies of the impact of haemodiafiltration on patient outcomes. She tells us what they found in this evidence pod.

Care delivery and self management strategies for adults with epilepsy

Mon, 05/23/2016 - 18:37

Epilepsy affects tens of millions of people around the world and alongside many trials and reviews of drugs and other treatments, are studies that have tested more complex strategies. In an updated Cochrane Review from February 2016, Peter Bradley, from Public Health Wales in the UK. and colleagues look at the evidence for some of these. He tells us what they found in this evidence pod.

Health system and community level interventions for improving antenatal care coverage and health outcomes

Mon, 05/23/2016 - 18:21

One of the major challenges facing the health systems of low and middle-income countries is to improve the antenatal care for pregnant women. In a new Cochrane Review from December 2015, Lawrence Mbuagbaw, from the Yaoundé Central Hospital in Cameroon and McMaster University in Canada, and colleagues have brought together the evidence on health system and community level interventions.

Effectiveness and safety of devices designed to close femoral artery puncture sites

Mon, 05/23/2016 - 17:14

A major development in health care in recent decades has been the ability of doctors to access difficult to reach parts of a patient’s body through their blood vessels. These endovascular procedures require access to the inside of an artery and need to finish by closing the hole that was created to enter the artery. The lead author of a new Cochrane Review in March 2016, Lindsay Robertson, from Freeman Hospital in Newcastle upon Tyne in the UK tells us about the evidence for one of the ways to do this.

Interventions for treating severe nausea and vomiting during pregnancy (hyperemesis gravidarum)

Thu, 05/12/2016 - 14:37

Many pregnant women will experience some degree of morning sickness, but, for some, the nausea and vomiting will be much worse. Rupsa Boelig from the Thomas Jefferson University Hospital in Philadelphia, USA tells us about the findings of a May 2016 Cochrane Review of interventions to help them.

Analysis bias

Tue, 05/10/2016 - 18:34

Mike Clarke, podcast editor for Trials Change Lives, based at the Northern Ireland Hub for Trials Methodology Research in Queen’s University Belfast discusses the general need to keep biases out of trials by looking at the specific challenge of minimizing bias when the results are being analyzed.

Read more on this topic in the James Lind Library.

This podcast is part of the Trials Change Lives initiative, developed by the MRC Network of Hubs for Trials Methodology Research in partnership with the Northern Ireland Network for Trials Methodology Research. Free posters are available to download methodologyhubs.mrc.ac.uk/research/trials-change-lives.

Exercise trials

Mon, 05/09/2016 - 19:33

Being physically active can have beneficial effects on our physical and mental health, but the UK population as a whole doesn’t meet the current Government guidelines. Dr Ruth Hunter, Lecturer in Physical Activity and Public Health/NIHR Career Development Fellow, UKCRC Centre of Excellence for Public Health, at Queen’s University Belfast in Northern Ireland describes some of the innovative approaches that her team are testing to encourage people to be more active.

This podcast is part of the Trials Change Lives initiative, developed by the MRC Network of Hubs for Trials Methodology Research in partnership with the Northern Ireland Network for Trials Methodology Research. Free posters are available to download methodologyhubs.mrc.ac.uk/research/trials-change-lives.