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Reconnecting Eye to Brain

Wed, 10/19/2016 - 20:29

Michael Crair, Yale University, and Carol Mason, Columbia University, have co-authored a report published online today in the Journal of Neuroscience. “Reconnecting Eye to Brain” is a comprehensive assessment of what scientists know about optic nerve development, regeneration, and reconnection. The report was based on input gathered during the Oct. 16, 2015, panel discussion, titled “Reconnecting Neurons in the Visual System,” sponsored by the National Eye Institute Audacious Goals Initiative (AGI). The panel comprised two dozen leading experts on neural development and regeneration. 

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Visual cortex plays role in plasticity of eye movement reflex

Wed, 10/12/2016 - 15:13

By peering into the eyes of mice and tracking their ocular movements, researchers made an unexpected discovery: the visual cortex – a region of the brain known to process sensory information – plays a key role in promoting the plasticity of innate, spontaneous eye movements. The study, published in Nature, was led by researchers at the University of California, San Diego (UCSD) and the University of California, San Francisco (UCSF) and funded by the National Eye Institute (NEI), part of the National Institutes of Health.

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Visual cortex plays role in plasticity of eye movement reflex

Wed, 10/12/2016 - 15:13

By peering into the eyes of mice and tracking their ocular movements, researchers made an unexpected discovery: the visual cortex – a region of the brain known to process sensory information – plays a key role in promoting the plasticity of innate, spontaneous eye movements. The study, published in Nature, was led by researchers at the University of California, San Diego (UCSD) and the University of California, San Francisco (UCSF) and funded by the National Eye Institute (NEI), part of the National Institutes of Health.

Language Undefined

Visual cortex plays role in plasticity of eye movement reflex

Wed, 10/12/2016 - 15:13

By peering into the eyes of mice and tracking their ocular movements, researchers made an unexpected discovery: the visual cortex – a region of the brain known to process sensory information – plays a key role in promoting the plasticity of innate, spontaneous eye movements. The study, published in Nature, was led by researchers at the University of California, San Diego (UCSD) and the University of California, San Francisco (UCSF) and funded by the National Eye Institute (NEI), part of the National Institutes of Health.

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U.S.-India joint effort targets genes and traits to improve glaucoma screening, prevention, and treatment

Tue, 10/04/2016 - 18:56

Researchers from the U.S. and India have begun a new collaborative project to identify genetic risk factors and traits related to glaucoma, a leading cause of blindness worldwide. Funded by the National Eye Institute (NEI), part of the National Institutes of Health (NIH), and India’s Department of Biotechnology (DBT), the researchers’ goal is to help develop effective screening, prevention, and treatment strategies for glaucoma.

U.S.-India joint effort targets genes and traits to improve glaucoma screening, prevention, and treatment

Tue, 10/04/2016 - 18:56

Researchers from the U.S. and India have begun a new collaborative project to identify genetic risk factors and traits related to glaucoma, a leading cause of blindness worldwide. Funded by the National Eye Institute (NEI), part of the National Institutes of Health (NIH), and India’s Department of Biotechnology (DBT), the researchers’ goal is to help develop effective screening, prevention, and treatment strategies for glaucoma.

U.S.-India joint effort targets genes and traits to improve glaucoma screening, prevention, and treatment

Tue, 10/04/2016 - 18:56

Researchers from the U.S. and India have begun a new collaborative project to identify genetic risk factors and traits related to glaucoma, a leading cause of blindness worldwide. Funded by the National Eye Institute (NEI), part of the National Institutes of Health (NIH), and India’s Department of Biotechnology (DBT), the researchers’ goal is to help develop effective screening, prevention, and treatment strategies for glaucoma.

Statement by NEI Director Paul A. Sieving, M.D., Ph.D., on National Academies’ report outlining public health strategies to promote and protect healthy vision for all Americans

Thu, 09/15/2016 - 20:07

Today, the National Academies of Sciences, Engineering, and Medicine (the National Academies) released “Making Eye Health A Population Health Imperative: Vision for Tomorrow.” The report culminates two years of in-depth analysis and discussion undertaken as a  consensus study on Public Health Approaches to Reduce Vision Impairment and Promote Eye Health .

Statement by NEI Director Paul A. Sieving, M.D., Ph.D., on National Academies’ report outlining public health strategies to promote and protect healthy vision for all Americans

Thu, 09/15/2016 - 20:07

Today, the National Academies of Sciences, Engineering, and Medicine (the National Academies) released “Making Eye Health A Population Health Imperative: Vision for Tomorrow.” The report culminates two years of in-depth analysis and discussion undertaken as a  consensus study on Public Health Approaches to Reduce Vision Impairment and Promote Eye Health .

Statement by NEI Director Paul A. Sieving, M.D., Ph.D., on National Academies’ report outlining public health strategies to promote and protect healthy vision for all Americans

Thu, 09/15/2016 - 20:07

Today, the National Academies of Sciences, Engineering, and Medicine (the National Academies) released “Making Eye Health A Population Health Imperative: Vision for Tomorrow.” The report culminates two years of in-depth analysis and discussion undertaken as a  consensus study on Public Health Approaches to Reduce Vision Impairment and Promote Eye Health .

Six teams seek to identify biological factors that influence neural regeneration

Thu, 09/01/2016 - 01:38

The National Institutes of Health will fund six projects to identify biological factors that affect neural regeneration in the retina. The projects are part of the National Eye Institute (NEI) Audacious Goals Initiative (AGI), a targeted effort to restore vision by regenerating neurons and their connections in the eye and visual system. These projects will receive a total of $12.4 million over three years, pending availability of funds. 

Six teams seek to identify biological factors that influence neural regeneration

Thu, 09/01/2016 - 01:38

The National Institutes of Health will fund six projects to identify biological factors that affect neural regeneration in the retina. The projects are part of the National Eye Institute (NEI) Audacious Goals Initiative (AGI), a targeted effort to restore vision by regenerating neurons and their connections in the eye and visual system. These projects will receive a total of $12.4 million over three years, pending availability of funds. 

Six teams seek to identify biological factors that influence neural regeneration

Thu, 09/01/2016 - 01:38

The National Institutes of Health will fund six projects to identify biological factors that affect neural regeneration in the retina. The projects are part of the National Eye Institute (NEI) Audacious Goals Initiative (AGI), a targeted effort to restore vision by regenerating neurons and their connections in the eye and visual system. These projects will receive a total of $12.4 million over three years, pending availability of funds. 

Drugs already on market prevent light-induced retinal degeneration in mice

Thu, 08/04/2016 - 22:10

Combinations of Food and Drug Administration-approved drugs protect against the loss of cells required for vision in a mouse model of blinding retinal diseases. The study, published in Science Signaling, was funded by the National Eye Institute, a part of the National Institutes of Health.

Drugs already on market prevent light-induced retinal degeneration in mice

Thu, 08/04/2016 - 22:10

Combinations of Food and Drug Administration-approved drugs protect against the loss of cells required for vision in a mouse model of blinding retinal diseases. The study, published in Science Signaling, was funded by the National Eye Institute, a part of the National Institutes of Health.

Use it or Lose it: Visual Activity Regenerates Neural Connections Between Eye and Brain

Fri, 07/08/2016 - 14:05

A study in mice funded by the National Institutes of Health (NIH) shows for the first time that high-contrast visual stimulation can help damaged retinal neurons regrow optic nerve fibers, otherwise known as retinal ganglion cell axons. In combination with chemically induced neural stimulation, axons grew further than in strategies tried previously. Treated mice partially regained visual function. The study also demonstrates that adult regenerated central nervous system (CNS) axons are capable of navigating to correct targets in the brain.

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Use it or Lose it: Visual Activity Regenerates Neural Connections Between Eye and Brain

Fri, 07/08/2016 - 14:05

A study in mice funded by the National Institutes of Health (NIH) shows for the first time that high-contrast visual stimulation can help damaged retinal neurons regrow optic nerve fibers, otherwise known as retinal ganglion cell axons. In combination with chemically induced neural stimulation, axons grew further than in strategies tried previously. Treated mice partially regained visual function. The study also demonstrates that adult regenerated central nervous system (CNS) axons are capable of navigating to correct targets in the brain.

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NEI Scientist Receives Research Grant from Knights Templar Eye Foundation

Fri, 07/01/2016 - 15:12

NEI research fellow Nathan Hotaling, PhD, has been awarded a $65,000 grant from the Knights Templar Eye Foundation to develop a stem cell-based system to study Best disease, a genetic disorder that can cause progressive vision loss. The system will allow researchers to develop tests to monitor cellular changes that lead to Best disease, which typically starts in childhood.

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NEI Scientist Receives Research Grant from Knights Templar Eye Foundation

Fri, 07/01/2016 - 15:12

NEI research fellow Nathan Hotaling, PhD, has been awarded a $65,000 grant from the Knights Templar Eye Foundation to develop a stem cell-based system to study Best disease, a genetic disorder that can cause progressive vision loss. The system will allow researchers to develop tests to monitor cellular changes that lead to Best disease, which typically starts in childhood.

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NIH Vision Scientists Test Theory of How Rods in our Retina Originated

Mon, 06/20/2016 - 17:27

Retinas from our earliest vertebrate ancestors had cone-like photoreceptors, presumably allowing them to see in daylight, but little ability to see at night. Then, millions of years ago in the Mesozoic era, and in relatively short order, mammals emerged that had retinas with predominantly rod photoreceptors, allowing for them to see at night perhaps to hunt for food while their dinosaur predators were dozing. Now a new study led by researchers the National Eye Institute suggests how the genesis of rod photoreceptors may have occurred to give rise to nocturnal mammals.

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