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Updated: 14 min 48 sec ago

NIH scientists deploy CRISPR to preserve photoreceptors in mice

Tue, 03/14/2017 - 18:58

Silencing a gene called Nrl in mice prevents the loss of cells from degenerative diseases of the retina, according to a new study. The findings could lead to novel therapies for preventing vision loss from human diseases such as retinitis pigmentosa. The study was conducted by researchers at the National Eye Institute (NEI), part of the National Institutes of Health, and was published online today in Nature Communications.  

NIH scientists deploy CRISPR to preserve photoreceptors in mice

Tue, 03/14/2017 - 18:58

Silencing a gene called Nrl in mice prevents the loss of cells from degenerative diseases of the retina, according to a new study. The findings could lead to novel therapies for preventing vision loss from human diseases such as retinitis pigmentosa. The study was conducted by researchers at the National Eye Institute (NEI), part of the National Institutes of Health, and was published online today in Nature Communications.  

 

Breast cancer drug dampens immune response, protecting light-sensing cells of the eye

Mon, 03/13/2017 - 20:53

The breast cancer drug tamoxifen appears to protect light-sensitive cells in the eye from degeneration, according to a new study in mice. The drug prevented immune cells from removing injured photoreceptors, the light-sensitive cells of the retina in the back of the eye. The study, recently reported in the Journal of Neuroscience, suggests tamoxifen might work for the treatment of age-related macular degeneration (AMD) and retinitis pigmentosa (RP), blinding diseases that lack good treatment options.

Breast cancer drug dampens immune response, protecting light-sensing cells of the eye

Mon, 03/13/2017 - 20:53

The breast cancer drug tamoxifen appears to protect light-sensitive cells in the eye from degeneration, according to a new study in mice. The drug prevented immune cells from removing injured photoreceptors, the light-sensitive cells of the retina in the back of the eye. The study, recently reported in the Journal of Neuroscience, suggests tamoxifen might work for the treatment of age-related macular degeneration (AMD) and retinitis pigmentosa (RP), blinding diseases that lack good treatment options.

NIH scientists identify disorder causing blindness, deafness, albinism and fragile bones

Wed, 03/01/2017 - 21:06

Researchers at the National Eye Institute (NEI), part of the National Institutes of Health, have identified the genetic underpinnings of a rare disorder that causes children to be born with deafness, blindness, albinism and fragile bones. The newly recognized syndrome, COMMAD, affects children who inherit two mutations of a gene – one from each parent – each of whom is deaf due to another rare, genetic disorder called Waardenburg syndrome 2A. A paper documenting the first recognized cases of COMMAD appears in the American Journal of Human Genetics(link is external). 

NIH scientists identify disorder causing blindness, deafness, albinism and fragile bones

Wed, 03/01/2017 - 21:06

Researchers at the National Eye Institute (NEI), part of the National Institutes of Health, have identified the genetic underpinnings of a rare disorder that causes children to be born with deafness, blindness, albinism and fragile bones. The newly recognized syndrome, COMMAD, affects children who inherit two mutations of a gene – one from each parent – each of whom is deaf due to another rare, genetic disorder called Waardenburg syndrome 2A. A paper documenting the first recognized cases of COMMAD appears in the American Journal of Human Genetics(link is external). 

NIH scientists identify disorder causing blindness, deafness, albinism and fragile bones

Tue, 02/28/2017 - 13:46

Researchers at the National Eye Institute (NEI), part of the National Institutes of Health, have identified the genetic underpinnings of a rare disorder that causes children to be born with deafness, blindness, albinism and fragile bones. The newly recognized syndrome, COMMAD, affects children who inherit two mutations of a gene – one from each parent – each of whom is deaf due to another rare, genetic disorder called Waardenburg syndrome 2A.

Five innovations harness new technologies for people with visual impairment, blindness

Fri, 02/03/2017 - 16:34

During Low Vision Awareness Month, the National Eye Institute (NEI), part of the National Institutes of Health, is highlighting new technologies and tools in the works to help the 4.1 million Americans living with low vision or blindness. The innovations aim to help people with vision loss more easily accomplish daily tasks, from navigating office buildings to crossing a street.

Five innovations harness new technologies for people with visual impairment, blindness

Fri, 02/03/2017 - 16:34

During Low Vision Awareness Month, the National Eye Institute (NEI), part of the National Institutes of Health, is highlighting new technologies and tools in the works to help the 4.1 million Americans living with low vision or blindness. The innovations aim to help people with vision loss more easily accomplish daily tasks, from navigating office buildings to crossing a street.

Stem cell secretions may protect against glaucoma

Thu, 01/26/2017 - 21:15

A new study in rats shows that stem cell secretions, called exosomes, appear to protect cells in the retina, the light-sensitive tissue in the back of the eye. The findings, published in Stem Cells Translational Medicine, point to potential therapies for glaucoma, a leading cause of blindness in the United States. The study was conducted by researchers at the National Eye Institute (NEI), part of the National Institutes of Health.

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Stem cell secretions may protect against glaucoma

Thu, 01/26/2017 - 21:15

A new study in rats shows that stem cell secretions, called exosomes, appear to protect cells in the retina, the light-sensitive tissue in the back of the eye. The findings, published in Stem Cells Translational Medicine, point to potential therapies for glaucoma, a leading cause of blindness in the United States. The study was conducted by researchers at the National Eye Institute (NEI), part of the National Institutes of Health.

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Reconnecting Eye to Brain

Wed, 10/19/2016 - 20:29

Michael Crair, Yale University, and Carol Mason, Columbia University, have co-authored a report published online today in the Journal of Neuroscience. “Reconnecting Eye to Brain” is a comprehensive assessment of what scientists know about optic nerve development, regeneration, and reconnection. The report was based on input gathered during the Oct. 16, 2015, panel discussion, titled “Reconnecting Neurons in the Visual System,” sponsored by the National Eye Institute Audacious Goals Initiative (AGI). The panel comprised two dozen leading experts on neural development and regeneration. 

Language Undefined

Reconnecting Eye to Brain

Wed, 10/19/2016 - 20:29

Michael Crair, Yale University, and Carol Mason, Columbia University, have co-authored a report published online today in the Journal of Neuroscience. “Reconnecting Eye to Brain” is a comprehensive assessment of what scientists know about optic nerve development, regeneration, and reconnection. The report was based on input gathered during the Oct. 16, 2015, panel discussion, titled “Reconnecting Neurons in the Visual System,” sponsored by the National Eye Institute Audacious Goals Initiative (AGI). The panel comprised two dozen leading experts on neural development and regeneration. 

Language Undefined

Reconnecting Eye to Brain

Wed, 10/19/2016 - 20:29

Michael Crair, Yale University, and Carol Mason, Columbia University, have co-authored a report published online today in the Journal of Neuroscience. “Reconnecting Eye to Brain” is a comprehensive assessment of what scientists know about optic nerve development, regeneration, and reconnection. The report was based on input gathered during the Oct. 16, 2015, panel discussion, titled “Reconnecting Neurons in the Visual System,” sponsored by the National Eye Institute Audacious Goals Initiative (AGI). The panel comprised two dozen leading experts on neural development and regeneration. 

Language Undefined

Visual cortex plays role in plasticity of eye movement reflex

Wed, 10/12/2016 - 15:13

By peering into the eyes of mice and tracking their ocular movements, researchers made an unexpected discovery: the visual cortex – a region of the brain known to process sensory information – plays a key role in promoting the plasticity of innate, spontaneous eye movements. The study, published in Nature, was led by researchers at the University of California, San Diego (UCSD) and the University of California, San Francisco (UCSF) and funded by the National Eye Institute (NEI), part of the National Institutes of Health.

Language Undefined

Visual cortex plays role in plasticity of eye movement reflex

Wed, 10/12/2016 - 15:13

By peering into the eyes of mice and tracking their ocular movements, researchers made an unexpected discovery: the visual cortex – a region of the brain known to process sensory information – plays a key role in promoting the plasticity of innate, spontaneous eye movements. The study, published in Nature, was led by researchers at the University of California, San Diego (UCSD) and the University of California, San Francisco (UCSF) and funded by the National Eye Institute (NEI), part of the National Institutes of Health.

Language Undefined

Visual cortex plays role in plasticity of eye movement reflex

Wed, 10/12/2016 - 15:13

By peering into the eyes of mice and tracking their ocular movements, researchers made an unexpected discovery: the visual cortex – a region of the brain known to process sensory information – plays a key role in promoting the plasticity of innate, spontaneous eye movements. The study, published in Nature, was led by researchers at the University of California, San Diego (UCSD) and the University of California, San Francisco (UCSF) and funded by the National Eye Institute (NEI), part of the National Institutes of Health.

Language Undefined

U.S.-India joint effort targets genes and traits to improve glaucoma screening, prevention, and treatment

Tue, 10/04/2016 - 18:56

Researchers from the U.S. and India have begun a new collaborative project to identify genetic risk factors and traits related to glaucoma, a leading cause of blindness worldwide. Funded by the National Eye Institute (NEI), part of the National Institutes of Health (NIH), and India’s Department of Biotechnology (DBT), the researchers’ goal is to help develop effective screening, prevention, and treatment strategies for glaucoma.

U.S.-India joint effort targets genes and traits to improve glaucoma screening, prevention, and treatment

Tue, 10/04/2016 - 18:56

Researchers from the U.S. and India have begun a new collaborative project to identify genetic risk factors and traits related to glaucoma, a leading cause of blindness worldwide. Funded by the National Eye Institute (NEI), part of the National Institutes of Health (NIH), and India’s Department of Biotechnology (DBT), the researchers’ goal is to help develop effective screening, prevention, and treatment strategies for glaucoma.

U.S.-India joint effort targets genes and traits to improve glaucoma screening, prevention, and treatment

Tue, 10/04/2016 - 18:56

Researchers from the U.S. and India have begun a new collaborative project to identify genetic risk factors and traits related to glaucoma, a leading cause of blindness worldwide. Funded by the National Eye Institute (NEI), part of the National Institutes of Health (NIH), and India’s Department of Biotechnology (DBT), the researchers’ goal is to help develop effective screening, prevention, and treatment strategies for glaucoma.

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